Effect of Time and Haemolysis on Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) Measurement on Blood Samples

Background: Coagulation, also known as blood clotting, is the process by which convert from a liquid to gel, forming clot. It referred haemostasis, stopping of loss damaged vessel, followed repair.
 Material and methods: This was cross sectional study conducted at albawasla medical laboratory, Khartoum, Sudan during period August November, 2021 evaluate effect time hemolysis on prothrombin activated partial thromboplastin tests. 50 samples (case group) were collected patients attending police teaching hospital requested PT APTT test in addition that,50 apparently healthy donors with no history any coagulation problems or chronic disease selected control group. Three ml venous container Tri Sodium Citrate anticoagulant. The tests (PT APTT) performed using semiautomatic device (coagulometer machine MI).
 Results: result this revealed that; when compared measurement immediately after one hour there insignificant differences (p. v.>0.05). between hemolyzed non-hemolyzed significant ( p. v.<0.05) case for immediately, hour, sample except age gender For correlation group samples.
 Conclusion: In cases results showed immediate 1 samples, gender, hr. APTT.
 Keywords: Homeostasis, sample,